Previous CiC awards

Jump to: Round 7 | Round 6 | Round 5 | Round 4 | Round 3 | Round 2 | Round 1

Round 7

Prof Perdita Barran, FSE
Smell-led volatile biomarker discovery from sebum and breath for tuberculosis diagnosis

Prof Brian Bigger, FBMH
Evaluation of genotoxicity & scale up transduction of HSC Gene Therapy for MPSII

Prof Giulio Cossu, FBMH
Immortal, universal donor cells for the ex vivo gene therapy of muscular dystrophy: development of a pre-clinical mouse model

Prof Tony Day, FBMH
Proof of concept for Link_TSG6 as a protein-based biologic for wet Age-Related Macular Degeneration (AMD)

Dr Mark Dunne, FBMH
Assay Detection for Focal Congenital Hyperinsulinism

Dr Katie Finegan, FBMH
Exploring the utility of targeting ERK5-signalling to treat idiopathic pulmonary fibrosis (IPF)

Prof Anthony Jones, FBMH
Neurofeedback platform for long-term use in patients with chronic arthritic pain

Prof Lydia Tabernero, FBMH
Development of anti-virulence agents for tuberculosis treatment

Prof Catharine West, FBMH
Translation of a hypoxia gene signature for use in bladder cancer onto a clinically applicable measurement platform

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Round 6

Professor Paul Bishop
Development of a novel treatment for age-related macular degeneration

Dr David Brough
Development of VRAC inhibitors as new anti-inflammatory agents

Dr Sam Butterworth
CCR2-targeted peptide-drug conjugates for the treatment of CMML

Dr Katie Finegan
Validation of a novel immunomodulatory approach to the treatment of Triple Negative Breast Cancer

Professor Nigel Hooper
Development of blood-based proteomic biomarkers of Alzheimer’s disease

Dr Sacha Howell
Automated Low Dose Risk Assessment Mammography (ALDRAM): defining breast cancer risk to reach the unreached

Dr Amir Keshmiri
Computer-Aided Surgical Planning (CASP): Feasibility of the First Surgical Planning Platform for Coronary Artery Bypass Grafting

Professor Susan Kimber
Validation of secreted markers and Biochip Assay development for use in clinical and commercial scaleup of pluripotent stem cells

Professor Qing-Jun Meng
Screening for Biomarkers in Synovial Fluid to Stratify Osteoarthritis Patients

Dr Laura Parkes
Dynamic glucose-enhanced (DGE)-MRI for non-invasive detection of altered blood-brain barrier glucose transport in dementia

Dr Anna Woollams
Can clinical imaging be used to predict the optimal type of therapy for aphasia?

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Round 5

Dr Michael Bromley (FBMH)
Investigation of Strathclyde minor groove binders as antifungal agents

Dr Simon J Clark (FBMH)
Optimisation of a novel chimeric protein to promote its cell secretion for the treatmentof age-related macular degeneration by gene therapy

Dr Paul Conroy (FBMH)
Development of ‘QuickWord’ Aphasia Software as a novel and promising approach to the treatment of Anomia after Stroke

Prof Bill Deakin (FBMH)
Do plasma proteomic patterns relate to CNS changes and predict syndromes and course of schizophrenia? Towards improved diagnosis and prognosis of schizophrenia

Prof Jeremy Derrick (FBMH)
A Novel Diagnostic Method to Stratify Anti-Drug Antibody Responses in Rheumatoid Arthritis Patients by Immunosignature Profiling

Dr John Gigg (FBMH)
Development of fenamate NLRP3 inflammasome inhibitors as potent treatments for the neuropathological, synaptic and cognitive symptoms of Alzheimer’s disease

Prof Ariane Herrick (FBMH)
Feasibility study of photoacoustic imaging for early diagnosis and risk stratification of severe digital ischaemia in systemic sclerosis-spectrum disorders

Professor Anthony Jones(FBMH)
Stimulating the brain to reduce chronic pain in the elderly

Dr Philip Murray (FBMH)
Using Gene Expression Data for the Diagnosis of Childhood Growth Hormone Deficiency

Ellen Poliakoff (FBMH)
Action Imagery and Observation in Neurorehabilitation for Parkinson’s Disease (ACTION-PD): User-informed development of a personalised home-based therapy

Dr Stephen Richardson (FBMH)
Self-healing, Biocompatible ‘NanoGlue’ for Repair of Meniscal Tears

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Round 4

Dr Brian Bigger (FMHS)
Validation of hematopoietic stem cell gene therapy for Mucopolysaccharidosis IIIB in human CD34+ stem cells

Dr Herve Boutin (FMHS)
Imaging of synaptic density in neurodegenerative conditions using PET-MR

Prof Silvia Bulfone-Paus (FMHS)
Mast cell activation assay – a robust and novel tool to diagnose clinical food allergy

Prof Garth Cooper (FMHS)
Elevated Copper in Human Diabetic Nephropathy: A New Therapeutic Target?

Prof Peter Gardner (FEPS)
Infrared Spectral Pathology on Glass Slides

Prof Alan Jackson (FBMH)
Using gallium labelled prostate specific membrane antigen (68GA PSMATHP) to guide patient selection for extended pelvic lymph-node dissection

Dr Meghna Jani (FMHS)
Development of a predictive tool for subsequent biologic response and adverse events in rheumatoid arthritis patients treated with TNF-a inhibitors

Dr Lucy Kershaw (FMHS)
Advanced characterisation of tumour hypoxia using PET-MRI to personalise radiotherapy for cervical cancer patient

Prof Harm van Marwijk (FMHS)
Kinectin frailty

Dr Adam J Reid (FMHS)
Advanced nerve guidance conduits for peripheral nerve repair

Prof Chris Taylor (FMHS)
Bringing quantitative nailfold capillaroscopy into the clinic

Prof Kaye Williams (FMHS)
Novel dual chemokine receptor inhibitors targeting endometrial cancer spread

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Round 3

Prof Paul Brenchley (FMHS)
Anti-PLA2R immunoadsorption therapy for membranous nephropathy patients

Prof Tony Day (FLS)
A novel therapeutic for OA: generation of new IP

Prof Jeremy Derrick (FLS)
Adaptation of a virus-like particle platform for high throughput vaccine antigen selection

Prof Rebecca Elliott (FMHS)
Cognitive biomarkers for drug development: evidence for psychopharmacological modulation of a novel test battery

Dr James Fildes (FMHS)
Increasing donor heart availability for transplantation using ex-vivo perfusion

Dr Alex Gerhard and Dr Sarah Skeoch (FMHS)
In vivo characterization of the inflammatory component of carotid plaques using PET/ CT and PET/MR in order to develop non-invasive prognostic imaging markers for stroke

Prof Judith Hoyland (FMHS)
The use of a semi-autologous structural bone graft to improve the clinical outcome of revision hip arthroplasty

Prof Ian Kimber (FLS) and Prof Chris Griffiths (FMHS)
Inhibition of epidermal Langerhans cell (LC) migration with soft drugs (SD) as a novel therapeutic strategy for the treatment of psoriasis

Dr Forbes Manson (FMHS)
Repositioning of urea cycle disorder drug for inherited retinal disease

Dr Andrea Murray (FMHS)
Pilot investigation of polarisation sensitive optical coherence tomography as a non-invasive measure of skin fibrosis

Dr Josephine Naish (FMHS)
MRI-based Diffusion Orientation Complexity (DOC) A Non-Invasive Novel Biomarker of cardiac fibrosis and heart failure

Dr Stephen Richardson (FMHS)
A novel regenerative therapy for IVD degeneration and treatment of low back pain

Prof Paul Townsend (FMHS)
Enriching biomarker identification – earlier diagnosis of Prostate Cancer

Prof Michael Turner (FEPS)
Automated prognostic cellular pattern recognition in pathology using multicoloured Luminsphere biolabels & multispectral microscopy

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Round 2

Prof Cay Kielty (FLS)
Developing cell/gene therapies for heritable fibrillinopathies

Prof Sonja Kotz (FMHS)
Towards a mobile health device for day-to-day monitoring of Parkinson’s disease

Prof Christopher Miller (FMHS)
To develop a novel treatment for hypertrophic cardiomyopathy

Prof Jo Neill (FMHS)
New target identification for neurodevelopmental disorders through development of a neuro immune animal model

Prof Ariane Herrick (FMHS)
Development of novel topical therapies for Raynaud’s phenomenon

Prof Rob Lucas (FLS)
Gene therapy to restore vision in retinal dystrophies

Dr Shane McKie (FMHS)
Improved drug discovery in psychiatry using arterial spin labeling based quantitative pharmacological magnetic resonance imaging

Dr Harmesh Aojula (FMHS)
Accelerating the early phase development of a new therapeutic for the treatment of small cell Lung cancer (SCLC)

Dr David Gilham (FMHS)
Chimeric Antigen Receptor (CAR) T-Cell Therapy for Ovarian Cancer

Dr Will Dixon (FMHS)
Development of a validated clinical and research tool for measuring musculoskeletal disease severity using passive motion and position sensing

Prof Shaheen Hamdy (FMHS)
Dysphagia in early stage Huntington’s disease: A multimodal imaging approach to target stimulation based therapies

Prof David Ray (FMHS) and Prof Andrew Loudon (FLS)
Identification of novel REV-ERB agonists with anti-inflammatory action

Dr David Brough (FLS)
Development of novel inflammasome inhibitors for the treatment of Alzheimer’s disease

Dr Lydia Tabernero (FLS)
A new treatment for tuberculosis by targeting MptpB phosphatase

Prof Mike Bromley (FMHS)
Development of a novel therapy to treat fungal infection

Prof Xin Wang (FLS)
Repositioning of an anti-epileptic drug for anti-arrhythmic treatment

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Round 1

Prof Paul Bishop (FMHS)
Optimisation of an anti-angiogenic opticin peptide for eye diseases

Dr Elizabeth Cartwright (FMHS)
Development of a novel therapeutic approach to cardiac hypertrophy and heart failure

Dr Curtis Dobson (FLS)
Development of point-of-care microbial safety monitors for peritoneal and haemodialysis patients

Prof Sue Kimber (FLS)
Chondrocytes from human embryonic stem cells for the clinical repair of cartilage defects

Dr Julie Gough (FEPS)
Resorbable magnesium alloys for bone repair applications

Dr Neil Pendleton (FMHS) and Prof. John Quinn (University of Liverpool)
Exploitation of Genome wide association markers for cognitive decline

Dr Laura Parkes (FMHS) and Prof. Graham Kemp (Liverpool)
Arterial Spin Labelled MRI – an imaging biomarker of cerebral blood flow in children

Dr Kim Linton (FMHS) and Prof. Andrew Pettit (Liverpool)
Molecular subtyping of diffuse large B-cell lymphoma (DLBCL) – developing a simple and inexpensive method for routine clinical use

Prof Robert Dryfe (FEPS)
Graphene as a vehicle for drug delivery

Dr Ardy Bayat (FMHS)
Role of Graphene combined with electrical stimulation in the acceleration of wound repair

Prof Steve Williams (FMHS)
Graphene-based MRI contrast agents

Dr Chris Blanford (FEPS)
Edge-specific reactions of biomolecules with graphene flakes on surfaces

Prof Jian Lu (FEPS)
Nanocomposite Graphene Biomaterials and Bionanofilm Platform

Prof Geoff Margison (FMHS)
Assessing graphene oxide as a matrix for DNA repair and DNA damage assays

Prof Ian Roberts (FLS)
Antimicrobial properties of graphene oxide

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